Categories
Articles

Nurturing our Future: The Vital Role of Health Supplements for Children

Nurturing our Future:
The Vital Role of Health Supplements for Children

In today’s fast-paced world, where hectic schedules and evolving dietary choices often dominate our lives, ensuring that children receive the essential nutrients they need can be quite a challenge. In this pursuit, the role of health supplements for children has gained increasing attention and significance.

Health supplements for children can help bridge the nutrient gap and ensure they receive all the vital elements they need for optimal growth. While a balanced diet should always be the primary source of nutrients, supplements can serve as a valuable complement, especially in cases where dietary choices are limited or specific nutrient requirements are not being met.

Activa offers a selection of child-safe health supplements designed to enhance both their development and overall well-being:

Activa is dedicated to ensuring the well-being and growth of the next generation. Our carefully crafted health supplements for children serve as a reliable complement to their daily nutrition. We firmly believe that by providing these essential elements, we contribute to the health, vitality, and brighter future of our young ones.

If you are interested to partner with Activa

Image Source: Canva
Categories
Articles

Clinical Observation: The Benefits of Activa Well Being Sleep

Clinical Observation:
The Benefits of Activa Well Being Sleep

Introduction and Purpose of the Study

In the U.S. alone sleep disorders disrupt and disturb the overall quality of life of more than 70 million people. From children to seniors, anyone can be affected. In fact, most of those who have sleep disorders are completely unaware of it. Many of those who are aware never choose to seek the help that they need[1].
Due to advances in the science of Sleep Medicine, help can be found for those who suffer from “bad sleep”. As indicated in “The International Classification of Sleep Disorders, Second Edition” documents, 81 sleep disorders have been officially classified. There are indeed many possible reasons for poor sleep.

The treatment depends on the reason for the issue. Implementing and following some basic sleep hygiene principles may help solve problems of physical or emotional discomfort[2]. When pain, illness, drugs, or stresses are the culprits, the cause must be treated. Sleep disorders, including sleep apneas, narcolepsy, primary insomnia, periodic limb movement disorder (PLMD), restless leg syndrome (RLS), and circadian rhythm sleep disorders, are also treatable.

There are numerous strategies and methods to cope with the physical or emotional discomfort of bad sleep, ranging from improved time and relationship management to daily life hygiene improvement (nutrition, exercise, sleep). The use of natural solutions, such as supplements with plant extracts, can bring some relief.

Laboratoires Activa intended to demonstrate the benefits of plant extracts on sleep. Their supplement for sleep: Well Being Sleep, was evaluated during a clinical observation conducted in an open practice set up on 10 voluntary patients, to demonstrate the benefits of the supplement on sleep.

Methods and Results

The patients were suffering from sleep disruptions for more than 3 months, and agreed to take 1 to 2 capsules of Activa Well Being Sleep daily for two months.
They were monitored during three months in total, with an assessment every 15 days to measure the outcome score and ensure compliance to the protocol.

The observation not only showed an improvement in the total amount of hours asleep but it also showed a reduction in general fatigue during the day and a reduction of night awakenings:

Total Amount of Hours Slept
More than 75% of the patients treated with Well Being Sleep recover more than two hours of sleep per night (now reporting six and more hours of sleep) in less than 60 days.

Frequency of Daytime Fatigue Sate
90% of the patients treated with Well Being Sleep will report the elimination of their daytime “sleepiness” in less than 60 days.

Night Awakenings
60% of patients reporting severe and frequent awakenings (four or more) have seen their condition improve.

 

Conclusion

Contact us to get more information on Activa Well Being Sleep and this observation

Sources:

[1] American Academy of Sleep. Sleep disorders : http://www.sleepeducation.com/Disorders.aspx
[2] Little, Nan (2007-01-01). “What Causes Sleep Difficulty?”. Insight Journal. Retrieved on 2008-01-25.

Image Source: Canva

Categories
Articles

Melatonin to reduce stress and anxiety

Melatonin to reduce stress and anxiety

Stress is natural. It is the organism’s innate physiological response to an unexpected event perceived as life threatening. It enables the body to quickly slow down “non-vital” functions and focus all possible energy and resources to fight or escape from this danger; this is commonly called the “flight or fight” response.

Adrenaline and cortisol: 2 hormones involved in stress

Adrenaline is a “warrior hormone” that mobilises all available energy to give the muscular strength to react.
Cortisol transforms fat into sugar and mobilises sugar energy to a specific location in the body. Some organs and functions then become secondary or “on hold”. When its level  returns to normal it will send a hunger response to the brain to replenish its reserves. In a regular situation, the cortisol maintains the energy balance of the body.

In a situation of recurrent stress, cortisol, and adrenaline are constantly secreted, which leads to a high heart rate, high blood pressure, and high blood sugar. The body constantly renews its reserves and stores them as fat. This continuous secretion can have a lot of negative consequences on health, such as diabetes and obesity, cardiovascular problems, memory disorders, learning difficulties, depression, and in case of cortisol depletion (adrenal fatigue) anxiety and exhaustion.

Melatonin: more than just a sleep hormone:

Melatonin is a hormone produced by the epiphysis gland, it is also called the sleep hormone. Its production is the antagonist to that of cortisol. It is secreted when the daylight reduces, inducing relaxation and preparing the body to sleep. Its peak secretion is around 3 am, but exposure to light affects its secretion and is one of the reasons people experience sleep difficulties when they travel as the exposure to light is changed and it affects natural melatonin secretion. For this reason, melatonin intake has been found to be very efficient in helping regulate the “sleep-wake” cycle. Moreover, with excessive exposure to non-natural light, the melatonin secretion of many individuals is disrupted, resulting in difficulties in falling asleep.

At night melatonin is released

Like a dance, cortisol, and melatonin follow a circadian rhythm and are therefore essential in the sleep and wake cycles. Cortisol induces activity in the body, it’s peak secretion is between 6 and 8 in the morning, just before waking up, whereas melatonin induces calm, secreted when night falls, with a peak secretion around 3 am. It has a strong action on anxiety and some studies have shown that when associated with light it decreases aggressive behavior. Getting ample natural sunlight is crucial as it directly affects the circadian rhythm, which, in turn, has a significant impact on our mood.

Studies have shown that melatonin plays a role in reducing stress-related psychological disturbances, anxiety, and agitation by bringing the circadian rhythm back in sync. This study has demonstrated the antidepressant potential of melatonin (1,2)

Melatonin goes beyond enhancing sleep quality; it can also alleviate stress, anxiety, and aggression, foster tranquility, and restore a sense of serenity.

The natural solution

Notes:

[1] 42. Jansen S, Forbes D, Duncan V, Morgan D, Malouf R. Melatonin for the treatment of dementia.Cochrane Database Syst Rev. 2011;(1):CD003802. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003802.pub3/abstract

[2] Detanico BC 1 , Piato AL , Freitas JJ , Lhullier FL , Hidalgo MP , Caumo W , ElisabetskyE .Antidepressant-like effects of melatonin in the mouse chronic mild stress model. EurJ Pharmacol 2009 1 avril; 607 (1-3): 121-5. doi: 10.1016 / j.ejphar.2009.02.037. Epub2009 le 26 février. https://pubmed.ncbi.nlm.nih.gov/19249298/

Image Source: Depositphotos

Categories
Articles

Melatonin, “The Sleep Hormone”

Melatonin, “The Sleep Hormone”

Melatonin, also called the “sleep hormone” is produced by the pineal gland at dusk. Melatonin thus plays a fundamental role in regulating our body clock as is responsible for the sleep/wake cycle.  The pineal gland is sensitive to light and production of melatonin will reduce in the morning to onset awakening. Taken in excess of 1 mg, it helps reduce the time it takes to fall asleep.

Melatonin is widely known to help your body adjust to jet lag. When you travel through different time zones your pineal gland doesn’t adjust straight away to the new dusk “time”, delaying your onset of sleep. Tricking the body by giving it melatonin helps adapt to the new time zone until your body adjusts its circadian cycle.

 

Not only inducing sleep, melatonin is known to also improve the quality of your sleep during periods of stress. Indeed the overall studies published since 2001 show it influences the time needed to fall asleep.

Melatonin works well to treat delayed sleep-phase disorder. This problem is related to a disturbance of the circadian rhythm. Sufferers fall asleep between 3 am to 6 am and wake up around midday  to 3 pm.

Researchers have found that people with certain health problems had melatonin levels below average. They have also made a connection with the consumption of melatonin during the day that could help reduce some psychological stress-related disorders such as depression, anxiety and agitation. Researchers conducted a study taking into account stress as a major contributing factor to depression and demonstrating the importance of resynchronization of circadian rhythms for effective treatment of depression. This study highlighted the melatonin potential as an antidepressant.

Finally, it has also been shown to help people suffering from migraine, irritable bowel syndrome  and fibromyalgia, as it can reduce chronic pain.

Consumption of melatonin at a reasonable dose is relatively safe, however it should be used with caution and moderation and restricted to short term use. Prolonged use could have some physiological side effect on your body’s natural production of melatonin. Your pineal gland could become lazy or stop its production if you substitute it with synthetic melatonin.

Sources:

  • Ballard CG, O’Brien JT, et al. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa.
  • Amsterdam JD1, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J., A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. Depression Research Unit, University Science Center.
  • Hanus M1, Lafon J, Mathieu M, Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders.
  • Étude sur l’Eschscholtzia californica menée par l’équipe du Laboratoire de Pharmacognosie de l’université de Metz .
  • Brzezinski A, Vangel MG, et al. Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Med Rev. 2005 Feb;9(1):41-50.10. Buscemi N, Vandermeer B, et al. The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis. J Gen Intern Med. 2005 Dec;20(12):1151-8.
  • Jansen S, Forbes D, Duncan V, Morgan D, Malouf R. Melatonin for the treatment of dementia.Cochrane Database Syst Rev. 2011;(1):CD003802. Résumé www2.cochrane.org
  • Detanico BC 1 , Piato AL , Freitas JJ , Lhullier FL , Hidalgo MP , Caumo W , Elisabetsky E .Antidepressant-like effects of melatonin in the mouse chronic mild stress model. Eur J Pharmacol 2009 1 avril; 607 (1-3): 121-5. doi: 10.1016 / j.ejphar.2009.02.037. Epub 2009 le 26 février.
  • The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis. van Geijlswijk IM, Korzilius HP, Smits MG. Sleep. 2010 Dec;33(12):1605-14.
  • Effect of melatonin administration on sleep, behavioral disorders and hypnotic drug discontinuation in the elderly: a randomized, double-blind, placebo-controlled study. Garzón C, Guerrero JM, et al. Aging Clin Exp Res. 2009 Feb;21(1):38-42.
  • Mcllwain H. Adenosine in neurohumoral · and regulatory roles in the brain. ln : Genazzani E, Herken H, eds. Central Nervous System – Studies on metabolic regulation and Junction. Berlin : Springer Verlag, 1973 : 3-11.
  • Harms HH, Wardeh G, Mulder AH. Effects of adenosine on depolarization induced release of various radiolabeled neurotransmitters from slices of rat corpus striatum. Neuroplw.muJCology 1979 ; 18 : 577-80.
  • Harms HH, Wardeh G, Mulder AH. Effects of adenosine on depolarization induced release of various radiolabeled neurotransmitters from slices of rat corpus striatum. Neuroplw.muJCology. 1979 ; 18 : 577-80.
  • Berne RM, Rubio R, Curnish RR. Release of adenosine from ischemie brain. Effect of cerebral vascular resistance and incorporation into cerebral adenine nucleotides. Circ Res 1974- ; 35 : 262-71.
  • Maitre M, Ciesielski L, Lehmann A, Kempf E, Mandel P. Protective effect of adenosine and nicotinamide against audiogenic seizure. Biochem Plw.muJCol 1974 ; 23 : 2807-16.
  • Jones P, Bachelard HS, Studies on amino acid metabolism in the brain using 15N-labeled precursors.

Image Source: Canva

Categories
Articles

Sleep key benefits for the Organism

Sleep key benefits for the Organism

We spend about a third of our lives sleeping. Sleeping is one of the body’s vital functions together with  breathing, digestion and immunity.

It has obviously been demonstrated, from observing sleep-deprived persons, that sleep is essential to maintain the functions of learning, memorization and adaptation to new circumstances. It also plays a key role in the state of well-being during the day.

Recent studies suggest that sleep helps maintain connections between neurons (synapses), thus consolidating innate and acquired memory. Sleep then favors the assimilation, storage and organization of new knowledge: these processes require the brain to be cut off from external stimuli.

Another sleep key benefit is to rest the organism or at least reduce its energy expenditure and the reconstitution of its metabolic energy stocks (glycogen contained in the liver). Other systems, such as the cardiovascular system, benefit from this “rest” time.

Anxiety, stress and depression are at the origin of more than half of insomnia cases. Other cases are due to challenges in lifestyle or environmental causes. An irregular rhythm of life or a noisy environment, for example, destructures sleep.

Occasional sleep disorders are linked to a particular event or a disturbing environment. When they become chronic, persisting over months or even years, their causes are most often psychological. They generally appear after a period of insomnia with a known cause and become psychophysiological. However, when the cause has disappeared, the insomnia persists through a conditioning mechanism that is mainly self-perpetuating due to the fear of not sleeping. It then evolves on its own.

Sleep disorders always have an impact on the quality of life during the day (2), and then on health: fatigue, irritability, mood, memory or concentration disorders, depression, etc…

The use of psychotic drugs is widely used to address sleep disorders, however it doesn’t offer a long term solution as it can create some serious dependencies and users may experience a “hangover” feeling when they wake up. Persistent and chronic sleep deprivation can harm health and getting medical advice is important. Finding the source of the stress, adjusting the lifestyle and the environment may offer a solution. The support of natural remedies such as herbal teas or natural plant based supplements containing soothing and relaxing plants that promote sleep can bring relief.

Promotes sleep and avoid night awakening

Synergy of Lime tree, Matricaria, Lemon Balm, Hawthorn and Eschscholzia

Each of these plants has active ingredients with their own properties, only a complex of those make possible to fight sleep disorders.

8 hours of efficiency, thanks to the extended release

Sources:
(1) https://www.youtube.com/watch?v=dqONk48l5vY
(2) Institut National du Sommeil et de la Vigilance
 
Image Source: Canva